Transfersome
Transfersome
Transfersome (pronunciation: /ˈtræns.fɚˌsoʊm/) is a type of liposome designed to deliver drugs across the skin barrier. The term "transfersome" is derived from the Latin transfers, meaning "to transfer", and the Greek soma, meaning "body".
Definition
A transfersome is a highly deformable, ultraflexible liposome that can penetrate the stratum corneum, the outermost layer of the skin. It is composed of phospholipids and edge activators, which give it its unique properties. Transfersomes are used in transdermal drug delivery systems to enhance the penetration of drugs through the skin.
History
The concept of transfersomes was first introduced in the early 1990s by Gregor Cevc and his colleagues. They were developed as a solution to the limitations of traditional liposomes, which are not able to penetrate the skin barrier effectively.
Applications
Transfersomes have a wide range of applications in the field of pharmaceuticals. They are used in the delivery of various types of drugs, including anti-inflammatory drugs, analgesics, and anticancer drugs. Transfersomes can also be used in the delivery of proteins and peptides, which are typically difficult to deliver through the skin.
Related Terms
External links
- Medical encyclopedia article on Transfersome
- Wikipedia's article - Transfersome
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