Transcription bubble
Transcription Bubble
The Transcription Bubble (pronunciation: /trænˈskrɪpʃən ˈbʌbəl/) is a crucial component in the process of transcription in both prokaryotic and eukaryotic organisms.
Etymology
The term "Transcription Bubble" is derived from the English words "transcription", which refers to the process of copying genetic information from DNA to RNA, and "bubble", which describes the shape of the open DNA strand during this process.
Definition
The Transcription Bubble is the region of the DNA double helix that is unwound and being actively transcribed by RNA polymerase. It is called a "bubble" because of the loop that forms when the two DNA strands separate, creating an open space or "bubble" in the DNA molecule.
Function
The main function of the Transcription Bubble is to provide a template for the synthesis of RNA. The RNA polymerase moves along the DNA strand, unwinding the double helix and creating the Transcription Bubble. As the RNA polymerase moves, the Transcription Bubble moves with it, allowing the RNA polymerase to add nucleotides to the growing RNA chain.
Related Terms
- DNA: Deoxyribonucleic acid, the molecule that carries genetic information in all living organisms.
- RNA: Ribonucleic acid, a molecule similar to DNA that plays a crucial role in protein synthesis and other chemical activities of the cell.
- RNA polymerase: An enzyme that synthesizes RNA by following a DNA template.
- Transcription: The process of copying genetic information from DNA to RNA.
External links
- Medical encyclopedia article on Transcription bubble
- Wikipedia's article - Transcription bubble
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