Toxophore
Toxophore
Toxophore (/tɒksəfɔːr/; from Greek τοξικός, 'toxic', and φέρειν, 'to bear') is a term used in pharmacology and biochemistry to denote the active part of a molecule that is responsible for its biological effects.
Etymology
The term 'toxophore' is derived from the Greek words 'toxikon' meaning 'poison' and 'pherein' meaning 'to bear'. It was first used in the late 19th century to describe the part of a molecule that is responsible for its toxic effects.
Function
In pharmacology, a toxophore is the part of a drug molecule that is responsible for its biological activity. This is often the part of the molecule that interacts with the target protein or enzyme in the body. The toxophore is usually a specific functional group or set of atoms within the molecule.
Related Terms
- Pharmacophore: The part of a molecular structure that is responsible for the biological activity of a drug.
- Haptophore: The part of a molecule that is responsible for its ability to bind to a target.
- Prodrug: A drug that is inactive in its administered form and must be metabolized in the body to produce the active drug.
- Enzyme: A protein that catalyzes chemical reactions in the body.
- Protein: A large molecule composed of one or more chains of amino acids.
See Also
External links
- Medical encyclopedia article on Toxophore
- Wikipedia's article - Toxophore
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