Toxicity category rating

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Toxicity Category Rating

Toxicity Category Rating (pronunciation: tɒkˈsɪsɪti kætəˈɡɔːri reɪtɪŋ) is a system used to classify the potential hazards of chemical substances to human health and the environment. The system is based on the severity of the toxic effects observed in toxicology studies.

Etymology

The term "toxicity" originates from the Greek word "toxikon," which means "poison," and "category rating" is derived from the Latin "categorizare," meaning "to classify."

Definition

Toxicity Category Rating is a classification system that ranks the potential hazards of chemical substances based on their toxic effects. The system is used in risk assessment and regulatory toxicology to determine the safety of chemicals for human health and the environment. The rating is usually given in numerical form, with Category I being the most toxic and Category IV being the least toxic.

Related Terms

  • Acute toxicity: The adverse effects of a substance that result either from a single exposure or from multiple exposures in a short period.
  • Chronic toxicity: The adverse effects of a substance that occur after a long period of exposure.
  • LD50: The dose of a substance that is lethal to 50% of a test population.
  • LC50: The concentration of a substance in air or water that is lethal to 50% of a test population.
  • No Observed Adverse Effect Level (NOAEL): The highest exposure level at which there are no biologically significant increases in the frequency or severity of adverse effect between the exposed population and its appropriate control.
  • Lowest Observed Adverse Effect Level (LOAEL): The lowest exposure level at which there are biologically significant increases in frequency or severity of adverse effects between the exposed population and its appropriate control.

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