Thogotovirus

Thogotovirus (tho-go-to-vi-rus, from the Thogoto forest in Kenya where it was first discovered) is a genus of viruses in the family Orthomyxoviridae. Thogotoviruses are known to infect a variety of hosts, including humans and other mammals, as well as ticks, which serve as the primary vector for transmission.

Etymology

The name Thogotovirus is derived from Thogoto forest in Kenya, where the first virus of this genus, Thogoto virus, was isolated in 1960. The name of the forest itself is a corruption of "Thogoto", the name of a local Kikuyu tribe.

Classification

Thogotoviruses are classified under the family Orthomyxoviridae, which also includes the genera Influenzavirus A, Influenzavirus B, Influenzavirus C, Influenzavirus D, Isavirus, Quaranjavirus, and Influenzavirus E.

Structure and Genome

Thogotoviruses are enveloped, with spherical geometries. The diameter is around 80-120 nm. Genomes are linear and segmented, around 6.4-6.9kb in length. The genome codes for 6 proteins.

Pathogenesis

Thogotoviruses are primarily transmitted through the bite of infected ticks. In humans, they can cause a range of symptoms, from mild fever to severe encephalitis. The severity of the disease can vary depending on the specific virus and the host's immune response.

Related Terms

• Orthomyxoviridae
• Influenzavirus A
• Influenzavirus B
• Influenzavirus C
• Influenzavirus D
• Isavirus
• Quaranjavirus
• Influenzavirus E

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