Thiamazole

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Thiamazole

Thiamazole (pronounced: thy-uh-muh-zohl), also known as Methimazole, is a medication primarily used to treat hyperthyroidism (overactive thyroid). It is a member of the thioamide group of drugs, which inhibit the production of thyroid hormones.

Etymology

The term "Thiamazole" is derived from its chemical structure, which includes a thioamide group (hence "thia") and an imidazole ring (hence "mazole").

Usage

Thiamazole is used to manage hyperthyroidism, a condition where the thyroid gland produces too much thyroid hormone. It works by inhibiting the enzyme thyroid peroxidase, which is involved in the production of thyroid hormones, thus reducing the levels of these hormones in the body.

Side Effects

Common side effects of Thiamazole include nausea, vomiting, loss of taste, and skin rash. In rare cases, it can cause more serious side effects such as agranulocytosis (a decrease in the number of white blood cells), hepatitis (inflammation of the liver), and vasculitis (inflammation of the blood vessels).

Related Terms

  • Hyperthyroidism: A condition in which the thyroid gland is overactive and makes excessive amounts of thyroid hormone.
  • Thioamide: A group of organic compounds that contain the functional group C(=S)NH2.
  • Thyroid peroxidase: An enzyme in the thyroid gland that plays a key role in the production of thyroid hormones.
  • Agranulocytosis: A condition characterized by a decrease in the number of white blood cells, which can lead to an increased risk of infection.
  • Hepatitis: Inflammation of the liver, usually caused by a viral infection or liver damage from alcohol or drugs.
  • Vasculitis: Inflammation of the blood vessels, which can cause problems in any organ system, including the skin, heart, lungs, kidneys, and nervous system.

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