Telmisartan/amlodipine

Telmisartan/amlodipine is a combination medication used in the treatment of hypertension (high blood pressure). It contains two active ingredients: telmisartan, an angiotensin II receptor antagonist, and amlodipine, a calcium channel blocker.

Composition

The medication is composed of two active ingredients:

• Telmisartan is an angiotensin II receptor antagonist that works by blocking the effects of a hormone called angiotensin II. This hormone causes blood vessels to narrow (constrict), which can lead to an increase in blood pressure. By blocking the effects of angiotensin II, telmisartan helps to relax and widen the blood vessels, thereby reducing blood pressure.

• Amlodipine is a calcium channel blocker that works by relaxing the muscles of the heart and blood vessels. This relaxation allows for greater blood flow and reduces the workload of the heart, thereby lowering blood pressure.

Indications

Telmisartan/amlodipine is indicated for the treatment of hypertension in patients who are not adequately controlled on monotherapy with either telmisartan or amlodipine, or in patients who have demonstrated clinical benefit from combination therapy.

Side Effects

Like all medications, telmisartan/amlodipine can cause side effects. Common side effects include dizziness, flushing, and swelling of the ankles or feet. More serious side effects can include a slow heartbeat, fainting, and a decrease in sexual ability.

Contraindications

Telmisartan/amlodipine is contraindicated in patients with known hypersensitivity to either telmisartan or amlodipine, and in patients with severe hepatic impairment.

Interactions

Telmisartan/amlodipine can interact with other medications, including other blood pressure medications, heart medications, and certain types of pain relievers. It is important for patients to inform their healthcare provider of all medications they are currently taking.

See Also

• Hypertension
• Angiotensin II receptor antagonist
• Calcium channel blocker