TOL101
TOL101 is an investigational immunotherapy drug that is currently being studied for its potential use in the prevention of organ transplant rejection. It is a monoclonal antibody that targets the alpha-beta T-cell receptor, which plays a crucial role in the immune response.
Mechanism of Action
TOL101 works by binding to the alpha-beta T-cell receptor on the surface of T cells. This prevents the T cells from recognizing and attacking the transplanted organ, thereby reducing the risk of organ rejection.
Clinical Trials
Several clinical trials have been conducted to evaluate the safety and efficacy of TOL101. These trials have shown promising results, with TOL101 demonstrating a good safety profile and potential efficacy in preventing organ rejection.
Potential Applications
If approved, TOL101 could be used in combination with other immunosuppressive drugs to prevent organ rejection in transplant patients. It could potentially improve the outcomes of organ transplants by reducing the risk of rejection and the associated complications.
See Also
References
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Contributors: Prab R. Tumpati, MD
