TAS2R31

TAS2R31 is a gene that encodes a protein known as a bitter taste receptor. This receptor is part of the TAS2R family, a group of proteins that are responsible for the detection of bitter compounds in the human mouth. The TAS2R31 gene is located on chromosome 12 in humans.

Function

The TAS2R31 gene encodes a protein that is a member of the TAS2R receptor family. These receptors are expressed in the taste buds of the tongue and are responsible for the detection of bitter compounds. The TAS2R31 receptor is particularly sensitive to certain bitter compounds, including phenylthiocarbamide (PTC) and propylthiouracil (PROP).

Genetics

The TAS2R31 gene is located on the long arm of chromosome 12 (12q24.31). It is one of approximately 30 TAS2R genes in the human genome. Variations in these genes are thought to contribute to individual differences in taste perception, particularly the perception of bitterness.

Clinical significance

Variations in the TAS2R31 gene have been associated with differences in taste perception, particularly the perception of bitterness. Some individuals, known as "supertasters," have a heightened sensitivity to bitter tastes, which is thought to be due in part to variations in TAS2R genes.

See also

• Taste receptor
• Bitter taste
• Phenylthiocarbamide
• Propylthiouracil
• Supertaster