Sudomotor
Sudomotor pertains to the processes and mechanisms that stimulate the sweat glands. Derived from the Latin words sudor meaning 'sweat' and motor, it is central to the body's thermoregulation and emotional responses.
Cholinergic Innervation
Cholinergic innervation plays a significant role in sudomotor activity. This refers to the aspect of the sympathetic nervous system that prominently affects sweat glands. Through this system, perspiration is triggered by the activation of muscarinic acetylcholine receptors.
Role of Acetylcholine and Nitric Oxide (NO)
Upon the release of acetylcholine, there is an induced vasodilation that takes place due to the presence of nitric oxide (NO). Vasodilation is the widening of blood vessels, which increases blood flow and ensures that sweat is produced efficiently.
Thermoregulation and Heat Loss
One of the primary functions of the sudomotor system is to aid in the body's thermoregulation. As blood flow increases due to vasodilation, sweat production also rises, facilitating heat loss via the skin. This mechanism ensures that the body maintains an optimal internal temperature, especially in situations where external temperatures might be elevated.
Emotional Responses and Blushing
Apart from thermoregulation, the sudomotor system is also involved in certain emotional responses. The brain's emotional centers exert control over sudomotor fibers, particularly those in the head, face, and upper chest regions. This connection is evident during blushing, a phenomenon where there is a noticeable reddening of the face and upper chest due to emotional triggers such as embarrassment or excitement.
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Contributors: Prab R. Tumpati, MD