Subplate

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Subplate

Subplate (pronunciation: /ˈsʌbpleɪt/) is a transient layer of cells in the cerebral cortex of the developing brain. It plays a crucial role in the establishment of cortical connectivity.

Etymology

The term "subplate" is derived from the Latin sub meaning "under" and plate, referring to the layer of cells beneath the cortical plate in the developing brain.

Definition

The subplate is a layer of cells located beneath the cortical plate in the developing brain. It is one of the first regions to differentiate in the cerebral cortex, and it plays a crucial role in the establishment of cortical connectivity. The subplate is involved in the guidance of thalamocortical axons and the formation of early cortical circuits.

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