Structural variation

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Structural Variation

Structural variation (pronunciation: /ˈstrʌktʃərəl ˌvɛəriˈeɪʃən/) is a term used in Genomics to describe the variation in the structure of an organism's chromosomal DNA sequence. This variation can include insertions, deletions, inversions, and translocations.

Etymology

The term "structural variation" is derived from the English words "structure" and "variation". "Structure" comes from the Latin word "structura" meaning "a fitting together, building". "Variation" comes from the Latin word "variatio" meaning "difference, diversity".

Related Terms

  • Copy number variation: A phenomenon in which sections of the genome are repeated and the number of repeats in the genome varies between individuals in the human population.
  • Single-nucleotide polymorphism: A substitution of a single nucleotide that occurs at a specific position in the genome, where each variation is present to some appreciable degree within a population.
  • Genetic variation: The difference in DNA among individuals or the differences between populations.
  • Genome: The genetic material of an organism, which consists of DNA (or RNA in RNA viruses).
  • Genetic recombination: The production of offspring with combinations of traits that differ from those found in either parent.

See Also

External links

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