Stewart–Treves syndrome
Stewart–Treves syndrome
Stewart–Treves syndrome (pronunciation: STEW-art TREH-ves sin-drome) is a rare cutaneous condition characterized by the development of lymphangiosarcoma, a type of soft tissue sarcoma, in patients with chronic lymphedema.
Etymology
The syndrome is named after the British physicians Edward Treves and Thomas Hodgkin Stewart, who first described the condition in 1948.
Definition
Stewart–Treves syndrome is defined as a lymphangiosarcoma (a rare form of lymphatic cancer) that develops in an area of the body affected by chronic lymphedema. This condition is most commonly associated with postmastectomy lymphedema, but it can also occur in other situations where lymphedema is present for a long period.
Symptoms
The main symptom of Stewart–Treves syndrome is the appearance of a red or purple patch of skin that gradually enlarges and becomes a raised, nodular, and ulcerated tumor. The tumor is usually painful and can bleed easily. Other symptoms may include fever, weight loss, and general malaise.
Diagnosis
Diagnosis of Stewart–Treves syndrome is based on clinical examination, patient history, and biopsy of the affected skin. Imaging tests such as MRI or CT scan may also be used to assess the extent of the disease.
Treatment
Treatment options for Stewart–Treves syndrome include surgery to remove the tumor, radiotherapy, and chemotherapy. However, the prognosis is generally poor due to the aggressive nature of the disease and its resistance to treatment.
Related Terms
External links
- Medical encyclopedia article on Stewart–Treves syndrome
- Wikipedia's article - Stewart–Treves syndrome
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