Stellate cells
Stellate Cells
Stellate cells (pronunciation: stel-late cells) are a type of cell found in the liver and pancreas. They are named for their star-like shape, with the term "stellate" deriving from the Latin word "stella," meaning star.
Etymology
The term "stellate" is derived from the Latin word "stella," which translates to "star" in English. This is in reference to the star-like shape of these cells.
Function
In the liver, stellate cells play a crucial role in the body's response to liver injury. They are responsible for the production of extracellular matrix proteins, including collagen, which can lead to the development of liver fibrosis if overproduced.
In the pancreas, stellate cells are involved in the development of pancreatitis and pancreatic cancer. They contribute to the fibrosis and inflammation associated with these conditions.
Related Terms
- Hepatic stellate cells: A type of stellate cell found in the liver.
- Pancreatic stellate cells: A type of stellate cell found in the pancreas.
- Fibrosis: The thickening and scarring of connective tissue, usually as a result of injury.
- Extracellular matrix: A three-dimensional network of extracellular macromolecules such as collagen and glycoproteins that provide structural and biochemical support to surrounding cells.
See Also
- Hepatology: The branch of medicine that incorporates the study of liver, gallbladder, biliary tree, and pancreas as well as management of their disorders.
- Gastroenterology: The branch of medicine focused on the digestive system and its disorders.
External links
- Medical encyclopedia article on Stellate cells
- Wikipedia's article - Stellate cells
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