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== Human anti-chimeric antibody == ...-ky-mehr-ik an-ti-bod-ee), often abbreviated as '''HACA''', is a type of [[antibody]] produced by the human immune system in response to the administration of

...odies]] (ANA) and [[Anti-double stranded DNA antibody|anti-double stranded DNA antibodies]] (anti-dsDNA), can suggest SLE and lupus nephritis.

...nt that prevents cell division by cross-linking DNA strands and decreasing DNA synthesis. ...works by intercalating DNA, disrupting the function of enzymes involved in DNA replication.

...autoantigen]]''' is a normal protein or complex of proteins (and sometimes DNA or RNA) that is recognized by the immune system of patients suffering from * '''[[Antigen]]''': A substance that binds to a specific antibody and causes an immune response.

* [[Antibody]] - a protein made by white blood cells that reacts with a specific foreign * [[DNA]] - deoxyribonucleic acid; responsible for passing genetic information in n