Sipple Syndrome

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Sipple Syndrome
TermSipple Syndrome
Short definitionSipple Syndrome - (pronounced) (SIH-pul SIN-drome) rare genetic disorder that affects the endocrine glands and causes a form of thyroid cancer called medullary thyroid cancer, pheochromocytoma, and parathyroid cancer. It can also cause benign (benign) tumors in the parathyroid and adrenal glands. 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


Sipple Syndrome - (pronounced) (SIH-pul SIN-drome) rare genetic disorder that affects the endocrine glands and causes a form of thyroid cancer called medullary thyroid cancer, pheochromocytoma, and parathyroid cancer. It can also cause benign (benign) tumors in the parathyroid and adrenal glands. The affected endocrine glands can produce high levels of hormones, which can lead to other medical problems like high blood pressure and kidney stones. An itchy skin condition may also occur. Sipple syndrome is caused by a mutation (change) in a gene called RET. Also referred to as MEN2A, MEN2A syndrome, multiple endocrine adenomatosis type 2A and multiple endocrine neoplasia type 2A syndrome

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