Microtome

Microtome is a tool used in microscopy to cut extremely thin slices of material, known as sections. They are an important device in medical research, forensic investigation, and in the diagnosis of diseases. The slices are often stained and then examined under a microscope.

History

The earliest devices were simply a sharp knife and a hand, but the development of the microtome led to the cutting of tissues into thin sections for microscopic examination. The first microtomes were made in 1770 by George Adams, Jr. and further developed in 1835 by Andrew Prichard.

Types of Microtomes

There are several types of microtomes, including the rotary microtome, cryomicrotome, ultramicrotome, vibrating microtome, and laser microtome. Each type has its own advantages and disadvantages, and is used for different purposes.

Uses

Microtomes are used in both clinical and research settings to prepare slides of tissue for viewing under a microscope. These slides can be used to diagnose diseases, such as cancer, and to research the effects of diseases on tissue structure.

See Also

• Histology
• Histopathology
• Pathology
• Microscopy

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