Sequence analysis
Sequence Analysis
Sequence analysis (pronunciation: /ˈsiːkwəns əˈnælɪsɪs/) is a method used in bioinformatics to study the genetic sequence of DNA, RNA, and protein to understand its evolution and function.
Etymology
The term "sequence analysis" is derived from the English words "sequence" which means a particular order in which related things follow each other, and "analysis" which means detailed examination of the elements or structure of something.
Definition
Sequence analysis involves the use of computational and statistical techniques to deduce biological information from genetic sequence data. It includes a wide range of methods such as alignment of sequences, phylogenetic analysis, motif detection, and gene prediction.
Related Terms
- Alignment of sequences: The process of arranging two or more sequences (of DNA, RNA, or protein sequences) in a specific order to identify regions of similarity that may be a consequence of functional, structural, or evolutionary relationships between the sequences.
- Phylogenetic analysis: The study of evolutionary relationships among groups of organisms, which is discovered through molecular sequencing data and morphological data matrices.
- Motif detection: The process of finding recurring patterns in DNA, RNA, or protein sequences. These motifs can have biological significance, such as DNA binding sites and protein interaction domains.
- Gene prediction: The process of identifying the regions of genomic DNA that encode genes. This is a critical step in annotating genomes.
See Also
External links
- Medical encyclopedia article on Sequence analysis
- Wikipedia's article - Sequence analysis
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