SPTB
SPTB
SPTB (pronounced as /ɛs.piː.tiː.biː/), also known as Spectrin Beta Chain, is a protein that in humans is encoded by the SPTB gene. It is a key component of the cytoskeletal structure of red blood cells (RBCs) and is involved in maintaining the elasticity and integrity of these cells.
Etymology
The term SPTB is an acronym derived from Spectrin Beta, referring to the beta chain of the spectrin protein. The name "spectrin" itself comes from the Latin "spectra", meaning "appearance", due to the protein's ghost-like appearance under the microscope.
Related Terms
- Spectrin: A type of protein found in the cytoskeleton of eukaryotic cells. It is made up of alpha and beta chains, including the SPTB.
- Cytoskeleton: A complex network of interlinking filaments and tubules that extend throughout the cytoplasm of a cell. It provides the cell with structure and shape.
- Red Blood Cells (RBCs): Also known as erythrocytes, these are the most common type of blood cell and the vertebrate organism's principal means of delivering oxygen to body tissues.
- SPTA1: The gene that encodes the alpha chain of the spectrin protein.
See Also
- Hereditary Elliptocytosis: A genetic disorder characterized by elliptically-shaped red blood cells, often caused by mutations in the SPTB gene.
- Hereditary Spherocytosis: A condition that affects red blood cells and is caused by a deficiency of proteins, including spectrin, that support the cell membrane.
External links
- Medical encyclopedia article on SPTB
- Wikipedia's article - SPTB
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