SLC22A10

SLC22A10 is a gene that encodes a protein in the human body. This protein is part of the solute carrier family 22 (organic anion/cation transporter), member 10. The SLC22A10 gene is located on chromosome 4q22.1.

Function

The protein encoded by the SLC22A10 gene is an integral membrane protein and is capable of transporting various substances across the cell membrane. These substances include organic anions and cations, which are important for many physiological processes. The protein is expressed in several tissues, including the liver, kidney, and intestine, where it plays a crucial role in the elimination of endogenous and exogenous substances.

Clinical Significance

Mutations in the SLC22A10 gene have been associated with various medical conditions. For instance, a study found that a variant of the SLC22A10 gene was associated with an increased risk of gout. Another study suggested that the SLC22A10 gene might be involved in the pathogenesis of type 2 diabetes.

Research

Research on the SLC22A10 gene is ongoing, with scientists aiming to understand more about its function and the role it plays in disease. This could potentially lead to the development of new treatments for conditions associated with mutations in the SLC22A10 gene.

See Also

• Solute carrier family
• Organic anion transporters
• Organic cation transporters

References

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