SARS2
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) is a novel coronavirus that was first identified in December 2019 in the city of Wuhan, China. It is the virus that causes the disease COVID-19, which has led to the ongoing COVID-19 pandemic.
Origin and Structure
SARS-CoV-2 is a member of the broader Coronaviridae family of viruses. It is believed to have originated in bats and jumped to humans via an intermediate host. The virus is enveloped and spherical in shape, with a core of single-stranded RNA. The virus's surface is covered in spike proteins, which it uses to enter human cells.
Transmission
SARS-CoV-2 is primarily transmitted between people through respiratory droplets and contact routes. Transmission can occur when an infected person coughs, sneezes, or talks, releasing droplets into the air that can be inhaled by people nearby. The virus can also spread if a person touches a surface or object that has the virus on it and then touches their mouth, nose, or eyes.
Symptoms and Complications
The symptoms of COVID-19 vary widely, but often include fever, cough, and difficulty breathing. Severe cases can lead to pneumonia, acute respiratory distress syndrome (ARDS), and death. Long-term complications of the disease are still being studied, but may include heart damage, lung damage, and neurological effects.
Prevention and Treatment
Prevention measures for SARS-CoV-2 include wearing masks, social distancing, and hand hygiene. Vaccines have also been developed and are being distributed globally. Treatment for COVID-19 primarily involves supportive care, though certain antiviral drugs have shown promise.
Impact
The impact of SARS-CoV-2 has been global and profound, affecting nearly every aspect of life. The virus has caused millions of deaths worldwide and has had significant economic, social, and psychological effects.
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Contributors: Prab R. Tumpati, MD