Moroctocog alfa
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Moroctocog alfa is a recombinant DNA derived, coagulation Factor VIII, intended for use in the treatment of hemophilia A. It is a blood-clotting protein that is used to prevent and control bleeding in patients with hemophilia A, a genetic disorder that prevents blood from clotting normally.
Overview
Moroctocog alfa is produced by recombinant DNA technology, which involves inserting the gene for human factor VIII into mammalian cells in a laboratory. The cells then produce factor VIII, which is purified and used as a medication. Moroctocog alfa is identical to the factor VIII that is naturally produced in the human body, and it works in the same way to help the blood clot.
Uses
Moroctocog alfa is used to prevent and control bleeding in patients with hemophilia A. It can be used to prevent bleeding during surgery or after an injury, and it can also be used to treat spontaneous bleeding episodes. Moroctocog alfa is also used as part of a prophylactic regimen to prevent bleeding episodes in patients with severe hemophilia A.
Side Effects
Like all medications, moroctocog alfa can cause side effects. The most common side effects include headache, fever, and allergic reactions. In rare cases, moroctocog alfa can cause serious side effects, such as the development of inhibitors (antibodies that neutralize the effect of the medication) and anaphylaxis (a severe allergic reaction).
Dosage
The dosage of moroctocog alfa is determined by the doctor based on the patient's weight, the severity of the hemophilia, the location and extent of bleeding, and the patient's clinical condition.
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Contributors: Prab R. Tumpati, MD