Quantitative computed tomography

From WikiMD's medical encyclopedia

Quantitative Computed Tomography (QCT) is a medical imaging procedure that uses computed tomography (CT) to quantify the amount of calcium in the bones to diagnose and monitor osteoporosis. It is also used to evaluate bone mineral density (BMD).

Overview

QCT is a type of CT that can provide accurate and precise measurements of the bone mineral density (BMD) in the spine and hip. Unlike dual-energy X-ray absorptiometry (DXA), QCT is able to distinguish between cortical and trabecular bone and can provide separate measurements for each.

Procedure

The QCT procedure involves a CT scan of the patient's spine or hip. The patient lies on a table that moves through the CT scanner, which takes a series of X-ray images from different angles. These images are then processed by a computer to create a three-dimensional (3D) image of the bone.

Applications

QCT is primarily used to diagnose and monitor osteoporosis, a condition that causes bones to become weak and brittle. It can also be used to assess the risk of fracture in patients with osteoporosis.

Advantages

One of the main advantages of QCT over other methods of measuring BMD is its ability to provide separate measurements for cortical and trabecular bone. This is important because these two types of bone have different rates of turnover, and osteoporosis affects them differently.

Limitations

Despite its advantages, QCT also has some limitations. It exposes patients to a higher dose of radiation than other methods of measuring BMD. It is also more expensive and less widely available than DXA.

See also

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Contributors: Prab R. Tumpati, MD