Propiconazole

An antifungal agent used in agriculture

Chemical Compound
Identifiers
CAS Number
PubChem CID
ChemSpider ID
UNII
ChEBI
ChEMBL
Properties
Chemical Formula
Molar Mass
Appearance
Density
Melting Point
Boiling Point
Hazards
GHS Pictograms	[[File:|50px]]
GHS Signal Word
GHS Hazard Statements
NFPA 704	[[File:|50px]]
References

Propiconazole is a triazole fungicide widely used in agriculture to protect crops from fungal diseases. It is known for its effectiveness in controlling a broad spectrum of fungal pathogens.

Chemical Properties

Propiconazole is a member of the triazole class of fungicides, which are characterized by their ability to inhibit the biosynthesis of ergosterol, an essential component of fungal cell membranes. The chemical structure of propiconazole includes a triazole ring, which is crucial for its antifungal activity.

Mode of Action

Propiconazole works by inhibiting the enzyme lanosterol 14_-demethylase, which is involved in the conversion of lanosterol to ergosterol. This inhibition disrupts the synthesis of ergosterol, leading to the accumulation of toxic sterol intermediates and ultimately causing cell membrane disruption and fungal cell death.

Applications

Propiconazole is used in a variety of agricultural settings, including the treatment of cereals, fruits, vegetables, and turf. It is effective against a range of fungal diseases such as rusts, powdery mildew, and leaf spots.

Safety and Environmental Impact

While propiconazole is effective in controlling fungal diseases, it is important to consider its safety and environmental impact. It is classified as a possible human carcinogen and should be handled with care. The use of propiconazole can also affect non-target organisms and should be managed to minimize environmental impact.

Regulation and Usage

The use of propiconazole is regulated in many countries to ensure safe application and to minimize risks to human health and the environment. Farmers and applicators are advised to follow label instructions and safety guidelines when using this fungicide.

Related pages

• Fungicide
• Triazole
• Ergosterol
• Agriculture