Porotic hyperostosis

From WikiMD's medical encyclopedia


Porotic hyperostosis
Synonyms Osteoporosis symmetrica, cribra orbitalia
Pronounce N/A
Specialty N/A
Symptoms Porous lesions on the skull, particularly the parietal bone and occipital bone
Complications Potential anemia
Onset Typically in childhood
Duration Chronic
Types N/A
Causes Often associated with iron deficiency anemia, malnutrition, or parasitic infections
Risks Nutritional deficiencies, genetic predisposition
Diagnosis Radiographic imaging, histological analysis
Differential diagnosis Osteoporosis, rickets, thalassemia
Prevention N/A
Treatment Addressing underlying nutritional deficiencies and anemia
Medication N/A
Prognosis Generally good with proper treatment
Frequency Common in archaeological populations
Deaths N/A


Porotic Hyperostosis is a pathological condition that affects the cranial vault, specifically the parietal and occipital bones. It is characterized by the presence of porous lesions on the skull, which are often associated with nutritional deficiencies, particularly iron deficiency anemia.

Etiology

The exact cause of Porotic Hyperostosis is not fully understood. However, it is believed to be associated with a variety of factors including malnutrition, particularly iron deficiency, and certain infectious diseases. Iron deficiency anemia is often cited as a primary cause, as it can lead to increased marrow activity in the skull, leading to the characteristic porosity.

Symptoms

The primary symptom of Porotic Hyperostosis is the presence of porous lesions on the skull. These lesions are often visible on the exterior of the skull, but can also be detected through radiographic imaging. Other symptoms may include fatigue, weakness, and pale skin, which are common symptoms of anemia.

Diagnosis

Diagnosis of Porotic Hyperostosis is typically made through physical examination and radiographic imaging. In some cases, a biopsy may be performed to confirm the diagnosis.

Treatment

Treatment for Porotic Hyperostosis primarily involves addressing the underlying cause. This may include dietary changes to increase iron intake, or treatment of any underlying infectious diseases. In severe cases, surgical intervention may be required to repair the skull.

See Also

References

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Contributors: Prab R. Tumpati, MD