Pork–cat syndrome

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Pork–cat syndrome
Synonyms
Pronounce N/A
Specialty N/A
Symptoms Allergic reactions after eating pork
Complications Anaphylaxis
Onset After sensitization to cat allergens
Duration
Types
Causes Cross-reactivity between cat albumin and pork albumin
Risks Cat ownership, exposure to cats
Diagnosis Skin prick test, specific IgE testing
Differential diagnosis Alpha-gal allergy, pork allergy
Prevention Avoidance of pork and cat allergens
Treatment Antihistamines, epinephrine for severe reactions
Medication
Prognosis
Frequency Rare
Deaths


Pork–cat syndrome is a rare type of allergy that is characterized by an allergic reaction to pork, often following the consumption of undercooked or raw pork. This condition is associated with a pre-existing sensitivity to cat dander.

Symptoms

The symptoms of Pork–cat syndrome can vary from person to person, but they typically include urticaria (hives), angioedema (swelling), rhinitis (runny nose), asthma, and anaphylaxis. These symptoms usually occur within a few minutes to a few hours after consuming pork.

Causes

Pork–cat syndrome is caused by an allergic reaction to a specific protein found in pork called albumin. People with this syndrome have a pre-existing allergy to cat dander, which contains a similar protein. When they consume pork, their immune system mistakenly identifies the pork albumin as the cat dander protein and triggers an allergic reaction.

Diagnosis

The diagnosis of Pork–cat syndrome is typically made based on the patient's history of allergic reactions after consuming pork and a positive skin prick test or blood test for pork and cat dander allergies.

Treatment

The primary treatment for Pork–cat syndrome is avoidance of pork. In cases where an allergic reaction occurs, treatment may include antihistamines, corticosteroids, and in severe cases, epinephrine.

See also

References

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Contributors: Prab R. Tumpati, MD