Plague vaccine

Plague vaccine is a vaccine used against Yersinia pestis to prevent plague. In the past, a live, attenuated vaccine has been used, but this is not currently recommended. The injectable vaccine is no longer commercially available.

Types

There are two types of plague vaccines: killed and live attenuated. The killed vaccine is made from Yersinia pestis bacteria that have been inactivated, while the live attenuated vaccine is made from a strain of Yersinia pestis that has been modified to reduce its virulence.

Killed Vaccine

The killed vaccine is made from Yersinia pestis bacteria that have been inactivated. This type of vaccine is no longer commercially available.

Live Attenuated Vaccine

The live attenuated vaccine is made from a strain of Yersinia pestis that has been modified to reduce its virulence. This type of vaccine is not currently recommended.

Effectiveness

The effectiveness of the plague vaccine is not well established. Some studies suggest that the vaccine may provide some protection against pneumonic plague, but it is not effective against bubonic plague.

Side Effects

The most common side effects of the plague vaccine are mild and include pain and swelling at the injection site, fever, and fatigue. Serious side effects are rare.

History

The first plague vaccine was developed in the late 19th century by Waldemar Haffkine. The vaccine was made from killed Yersinia pestis bacteria and was used during outbreaks of plague in India.

See Also

• Yersinia pestis
• Plague
• Vaccine
• Waldemar Haffkine

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  Man being injected by doctor, during the outbreak of bubonic