Placental cotyledon
== Placental Cotyledon ==
A placental cotyledon is a structural and functional unit of the placenta in mammals. It is a subdivision of the placenta, which is essential for the exchange of nutrients, gases, and waste products between the mother and the fetus.
Structure
The placental cotyledon is composed of a mass of villi that are grouped together. These villi are finger-like projections that extend into the maternal blood space, allowing for the exchange of substances. Each cotyledon is supplied by a branch of the umbilical artery and drained by a branch of the umbilical vein.
Function
The primary function of the placental cotyledon is to facilitate the exchange of oxygen, carbon dioxide, nutrients, and waste products between the maternal and fetal blood. This exchange occurs across the placental barrier, which is a thin layer of tissue that separates the maternal and fetal blood supplies.
Development
The development of placental cotyledons begins early in pregnancy. The trophoblast cells of the blastocyst invade the maternal endometrium, forming the initial structure of the placenta. As the placenta matures, the villi become more branched and form distinct cotyledons.
Clinical Significance
Abnormalities in the structure or function of placental cotyledons can lead to complications in pregnancy, such as placental insufficiency, intrauterine growth restriction, and preeclampsia. Proper functioning of the cotyledons is crucial for the health and development of the fetus.
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References
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Contributors: Prab R. Tumpati, MD