Piperonyl butoxide
Piperonyl butoxide (PBO) is a chemical compound often used as a synergist in the application of insecticides. It is a semi-synthetic derivative of safrole.
History
Piperonyl butoxide was first registered in the United States in 1957. It was initially used in combination with pyrethrins, a class of naturally occurring insecticides, to enhance their effectiveness.
Chemistry
Piperonyl butoxide is an organic compound that is classified as a waxy solid at room temperature. It has a slight, characteristic odor. The chemical formula for piperonyl butoxide is C19H30O5.
Mode of Action
Piperonyl butoxide works by inhibiting the natural defense mechanisms of insects. It blocks the action of enzymes that would otherwise break down the insecticides before they can take effect. This allows the insecticides to be more effective.
Uses
Piperonyl butoxide is used in a variety of insecticide products, including those for home, garden, and veterinary use. It is often combined with other insecticides such as permethrin, tetramethrin, and resmethrin.
Safety and Environmental Impact
While piperonyl butoxide is not considered highly toxic to humans or animals, it can cause irritation if it comes into contact with the skin or eyes. It is also toxic to fish and other aquatic organisms.
Regulation
In the United States, products containing piperonyl butoxide are regulated by the Environmental Protection Agency (EPA). The EPA classifies piperonyl butoxide as a Group C, possible human carcinogen.
See Also
This insecticide-related article is a stub. You can help WikiMD by expanding it.
Piperonyl_butoxide
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Contributors: Prab R. Tumpati, MD