Pinatuzumab vedotin

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Pinatuzumab Vedotin

Pinatuzumab Vedotin (pronunciation: pi-na-tu-zu-mab ve-do-tin) is a type of antibody-drug conjugate used in the treatment of cancer. It is currently under investigation for its potential use in treating non-Hodgkin lymphoma and diffuse large B-cell lymphoma.

Etymology

The name "Pinatuzumab Vedotin" is derived from its components. "Pinatuzumab" is a monoclonal antibody that targets the protein CD22, which is often found on the surface of B cells. "Vedotin" refers to the drug that is attached to the antibody, which is designed to kill cancer cells.

Mechanism of Action

Pinatuzumab Vedotin works by binding to the CD22 protein on the surface of B cells. Once bound, the drug is internalized by the cell, where it releases its cytotoxic payload. This causes the cell to die, reducing the number of cancerous B cells in the body.

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