Picoplatin
Picoplatin
Picoplatin (pronounced: pee-koh-pla-tin) is a platinum-based chemotherapy drug used in the treatment of various types of cancer. It is a third-generation platinum compound that was designed to overcome resistance to previous platinum-based drugs.
Etymology
The term "Picoplatin" is derived from the words "pico", meaning very small in the International System of Units, and "platinum", referring to the platinum-based compound used in the drug.
Mechanism of Action
Picoplatin works by interfering with the DNA in cancer cells, preventing them from dividing and growing. It forms covalent bonds with the DNA, causing the DNA strands to cross-link, which inhibits DNA replication and transcription.
Uses
Picoplatin is used in the treatment of various types of cancer, including lung cancer, ovarian cancer, and testicular cancer. It is often used when other platinum-based chemotherapy drugs, such as cisplatin and carboplatin, have failed.
Side Effects
Common side effects of picoplatin include nausea, vomiting, diarrhea, and fatigue. More serious side effects can include neutropenia, a condition characterized by low levels of neutrophils, a type of white blood cell.
Related Terms
- Chemotherapy
- Platinum-based chemotherapy
- DNA
- Cancer
- Lung cancer
- Ovarian cancer
- Testicular cancer
- Cisplatin
- Carboplatin
- Neutropenia
External links
- Medical encyclopedia article on Picoplatin
- Wikipedia's article - Picoplatin
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