Phacodonesis
Phacodonesis is a medical condition that involves the shaking or trembling of the lens in the eye. This condition is often associated with various eye diseases and conditions, such as cataracts, glaucoma, and uveitis. It can also occur as a result of aging or trauma to the eye.
Causes
Phacodonesis can be caused by a variety of factors. The most common cause is the weakening of the zonules of Zinn, which are the fibers that hold the lens in place. This can occur as a result of aging, trauma to the eye, or certain diseases such as Marfan syndrome or Weill-Marchesani syndrome.
Other causes can include:
- Cataract surgery, which can sometimes damage the zonules and cause the lens to become unstable.
 - Glaucoma, a condition that increases pressure in the eye and can weaken the zonules.
 - Uveitis, an inflammation of the middle layer of the eye, which can also damage the zonules.
 
Symptoms
The main symptom of phacodonesis is the shaking or trembling of the lens, which can be seen during an eye examination. This can cause blurred vision, especially when the eye is moving. Other symptoms can include:
- Difficulty focusing on objects, especially those that are close up.
 - Seeing halos around lights.
 - Sensitivity to light.
 
Treatment
Treatment for phacodonesis depends on the underlying cause. If the condition is caused by a disease such as glaucoma or uveitis, treating the disease can often alleviate the symptoms of phacodonesis. In some cases, surgery may be necessary to stabilize the lens or to replace it with an artificial one.
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Contributors: Prab R. Tumpati, MD