Pericardial heart valves
An overview of pericardial heart valves used in cardiac surgery
Pericardial Heart Valves
Pericardial heart valves are a type of bioprosthetic heart valve used in cardiac surgery to replace diseased or dysfunctional heart valves. These valves are constructed from the pericardium, which is the fibrous sac surrounding the heart, typically sourced from bovine or porcine tissue. Pericardial valves are designed to mimic the function of natural heart valves, allowing for unidirectional blood flow and preventing backflow.
Structure and Composition
Pericardial heart valves are composed of leaflets made from treated pericardial tissue. The pericardium is chemically treated to reduce immunogenicity and increase durability. The leaflets are mounted on a supporting stent, which is often made of metal or polymer, and the entire assembly is sewn into a fabric-covered sewing ring that allows for secure attachment to the heart tissue.
Function
The primary function of pericardial heart valves is to replace the function of the native heart valves, which may be compromised due to conditions such as aortic stenosis, mitral regurgitation, or other valvular heart diseases. These prosthetic valves open and close with each heartbeat, ensuring that blood flows in the correct direction through the heart chambers and into the systemic circulation.
Advantages
Pericardial heart valves offer several advantages over mechanical heart valves, including:
- Reduced need for anticoagulation: Patients with pericardial valves typically require less aggressive anticoagulation therapy compared to those with mechanical valves, reducing the risk of bleeding complications.
- Hemodynamic performance: These valves often provide excellent hemodynamic performance, closely mimicking the natural flow dynamics of the heart.
- Biocompatibility: The use of biological tissue reduces the risk of rejection and other immune responses.
Disadvantages
Despite their benefits, pericardial heart valves have some limitations:
- Durability: They may have a shorter lifespan compared to mechanical valves, often requiring replacement after 10-20 years, especially in younger patients.
- Calcification: Over time, the tissue can calcify, leading to reduced valve function and potential failure.
Surgical Considerations
The implantation of a pericardial heart valve is a complex surgical procedure that requires careful consideration of the patient's anatomy and the specific valve being replaced. Surgeons must ensure proper sizing and positioning to optimize valve function and longevity.
Postoperative Care
Patients with pericardial heart valves require regular follow-up to monitor valve function and detect any complications early. Echocardiography is commonly used to assess valve performance and detect issues such as regurgitation or stenosis.
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Contributors: Prab R. Tumpati, MD