Percutaneous hepatic perfusion
Percutaneous Hepatic Perfusion (per-kyoo-TAY-nus heh-PAT-ik per-FYOO-shun) is a medical procedure used primarily in the treatment of liver cancer and metastatic liver disease. The term originates from the Latin percutaneus meaning "through the skin", hepaticus meaning "of the liver", and perfusio meaning "a pouring over".
Procedure
Percutaneous hepatic perfusion (PHP) involves the delivery of high doses of chemotherapy drugs directly to the liver. This is achieved by isolating the liver's blood supply from the rest of the body, thus minimizing systemic exposure and potential side effects. The procedure is performed under radiological guidance by an interventional radiologist.
Indications
PHP is typically indicated for patients with unresectable liver tumors, either primary or metastatic. It is also used in cases where systemic chemotherapy has failed or is not tolerated.
Benefits and Risks
The main benefit of PHP is the ability to deliver high doses of chemotherapy directly to the liver, potentially improving tumor response and patient survival. However, like all medical procedures, PHP carries risks, including potential damage to the liver and other organs, infection, and complications related to chemotherapy.
See Also
External links
- Medical encyclopedia article on Percutaneous hepatic perfusion
- Wikipedia's article - Percutaneous hepatic perfusion
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