Pentachloronitrobenzene
Pentachloronitrobenzene (PCNB), also known as Quintozene, is a fungicide used to control a wide range of fungi that affect plants, particularly turf grasses. It is a member of the organochlorine class of pesticides, which also includes substances such as DDT and lindane.
Chemical Structure and Properties
Pentachloronitrobenzene is a yellow, crystalline solid with a slight, characteristic odor. It is nonflammable and does not dissolve easily in water. The chemical formula for PCNB is C6Cl5NO2, and its molecular weight is 295.33 g/mol. It belongs to the class of organochlorine compounds, which are characterized by the presence of chlorine atoms in their molecular structure.
Uses
PCNB is primarily used as a fungicide in the agricultural sector. It is effective against a wide range of fungi, including those that cause diseases such as root rot, damping off, and snow mold. It is also used in the treatment of seeds, particularly those of cotton, sunflower, and soybean.
Health Effects
Exposure to PCNB can cause a variety of health effects. Acute exposure can lead to irritation of the skin, eyes, and respiratory tract. Chronic exposure can result in damage to the liver, kidneys, and central nervous system. It is also classified as a possible human carcinogen by the International Agency for Research on Cancer (IARC).
Environmental Impact
Like other organochlorine pesticides, PCNB is persistent in the environment and can accumulate in the food chain. It is toxic to aquatic organisms and can cause long-term adverse effects in the aquatic environment.
Regulation
Due to its potential health and environmental impacts, the use of PCNB is regulated in many countries. In the United States, it is classified as a Restricted Use Pesticide (RUP) by the Environmental Protection Agency (EPA).
See Also
Pentachloronitrobenzene
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Contributors: Prab R. Tumpati, MD