Pendetide

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Pendetide

Pendetide (pronunciation: pen-de-tide) is a synthetic peptide used in medical imaging. It is primarily used in the detection and localization of neuroendocrine tumors.

Etymology

The term "Pendetide" is derived from the combination of the words "Pentetreotide" and "Iodide". "Pentetreotide" is a synthetic analogue of the hormone somatostatin, and "Iodide" refers to the radioactive iodine isotope used in the imaging process.

Usage

Pendetide is used in conjunction with a radioactive tracer, usually Indium-111, to create images of certain types of tumors. The Pendetide binds to the tumor cells, and the radioactive tracer makes these cells visible on a gamma camera. This process is known as Octreoscan.

Related Terms

  • Somatostatin: A hormone that inhibits the release of growth hormone and insulin from the pancreas.
  • Neuroendocrine tumor: A type of tumor that originates from the neuroendocrine cells in the body.
  • Gamma camera: A device used in nuclear medicine imaging to capture the radiation from a patient after they have been injected with a small amount of radioactive tracer.
  • Indium-111: A radioactive isotope of indium, used as a tracer in nuclear medicine.
  • Octreoscan: A type of imaging test that uses a radioactive tracer to detect certain types of tumors.

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