Pedigree

Pedigree is a term used in genetics to describe the family history of an individual, particularly with regard to their inherited traits or diseases. It is a graphical representation of a family tree that displays detailed genetic information. It is used to analyze patterns of inheritance for specific genetic traits or diseases.

Overview

A pedigree chart is a diagram that shows the occurrence and appearance of phenotypes of a particular gene or organism and its ancestors from one generation to the next, most commonly humans, show dogs, and race horses. The word pedigree is a corruption of the French "pied de grue" or crane's foot, because the typical lines and split lines (each split leading to different offspring of the one parent line) resemble the thin leg and foot of a crane.

Use in Genetics

In medicine and genetics, a detailed pedigree can be used to discover patterns of inheritance of traits. This can help to calculate the probability of a child inheriting a specific trait or disease. It is also used to help identify potential genetic disorders or diseases before they occur, and can assist in the planning and implementation of an individual's health care.

Symbols

Pedigree charts are often used to show the transmission of genetic disorders. A series of standard symbols are used in these charts to represent individuals, relationships, and the presence or absence of the genetic condition.

See Also

• Genogram
• Family tree
• Genetics
• Medical genetics

References

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