Paget

Paget's disease is a medical condition that disrupts the normal cycle of bone renewal, causing bones to become weak and deformed. There are two main types: Paget's disease of bone and Paget's disease of the breast.

Paget's disease of bone

Paget's disease of bone is a chronic disorder that can result in enlarged and misshapen bones. The excessive breakdown and formation of bone tissue causes affected bone to weaken, resulting in pain, misshapen bones, fractures, and arthritis in the joints near the affected bones.

Symptoms

Often, Paget's disease of bone has no symptoms. However, common symptoms when they do occur include bone pain, joint pain (due to the disease affecting bones near a joint), bone deformities, and complications such as broken bones and nerve problems.

Causes

The cause of Paget's disease of bone is unknown, but genetic factors and certain viral infections may be associated with its development.

Treatment

Treatment includes medications to control the disease and manage symptoms. In some cases, surgery may be needed to treat fractures or severe deformities.

Paget's disease of the breast

Paget's disease of the breast is a rare type of cancer that forms in or around the nipple and frequently extends to the areola.

Symptoms

Symptoms include redness and irritation of the nipple and areola, flaky or scaly skin on the nipple, discharge from the nipple, and a lump in the breast.

Causes

The exact cause of Paget's disease of the breast is unknown. However, most researchers agree that it's likely due to an underlying ductal breast cancer.

Treatment

Treatment typically involves surgery to remove the cancer. Radiation therapy, chemotherapy, or hormone therapy may also be used.

See also

• Bone disease
• Breast cancer

References

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