Original

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Original

Original (pronunciation: /əˈrɪdʒɪnəl/), from the Latin word originem meaning "beginning, source, birth", is a term often used in various fields of study, including medicine. It refers to something that is the first of its kind, or the source from which other things are derived or developed.

Medical Usage

In the field of medicine, the term "original" is often used to refer to the primary source of a disease or condition, or the first occurrence of a symptom or sign. For example, in the study of epidemiology, the "original" case of a disease outbreak is often referred to as the "index case" or "patient zero".

In genetics, an "original" mutation is the first mutation that occurs in a gene, which can then be passed on to subsequent generations. Similarly, in pharmacology, an "original" drug is the first version of a medication that is developed, before any generic versions or derivatives are created.

Related Terms

  • Index case: The first identified case in a group of related cases of a particular communicable or heritable disease.
  • Patient zero: The initial patient in the population of an epidemiological investigation, or more generally, the first case of a condition or syndrome to be described in the medical literature.
  • Mutation: A change in a DNA sequence, usually occurring because of errors in replication or repair.
  • Pharmacology: The branch of medicine concerned with the uses, effects, and modes of action of drugs.

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