Ombrabulin
Ombrabulin
Ombrabulin (pronunciation: om-bra-byoo-lin) is a synthetic, water-soluble antineoplastic agent that is used in the treatment of various types of cancer. It is a vascular disrupting agent (VDA) that selectively targets the vasculature of cancer cells, leading to their death.
Etymology
The term "Ombrabulin" is derived from the combination of the words 'ombra', which is Italian for 'shadow', and 'bulin', which is a common suffix used in the naming of antineoplastic agents. The name signifies the drug's ability to cast a 'shadow' over cancer cells, effectively disrupting their growth.
Mechanism of Action
Ombrabulin works by disrupting the vasculature of cancer cells. It binds to the tubulin in the cells, causing the vasculature to collapse and leading to cell death. This mechanism of action is different from other antineoplastic agents, which typically work by inhibiting cell division.
Related Terms
- Antineoplastic agent: A substance that inhibits the growth and spread of cancerous or potentially cancerous cells.
- Vasculature: The arrangement of blood vessels in an organ or tissue.
- Tubulin: A protein that is a major component of microtubules, which are a component of the cell's cytoskeleton.
See Also
External links
- Medical encyclopedia article on Ombrabulin
- Wikipedia's article - Ombrabulin
This WikiMD article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski