Odontogenic keratocyst

Odontogenic Keratocyst

The Odontogenic keratocyst (pronunciation: /oʊˌdɒntoʊˈdʒɛnɪk ˌkɛrətoʊˈsɪst/), also known as OKC, is a type of cyst that originates from the odontogenic (tooth-forming) tissue. The term "odontogenic" is derived from the Greek words "odonto" meaning tooth and "genic" meaning origin or formation.

Definition

An Odontogenic keratocyst is a benign intraosseous lesion of odontogenic origin. It is characterized by its unique histopathological appearance and has a high recurrence rate.

Etiology

The exact etiology of OKC is unknown. However, it is believed to arise from the dental lamina or its remnants. It is also associated with the nevoid basal cell carcinoma syndrome (NBCCS), a rare genetic disorder.

Clinical Features

Clinically, OKC often presents as a painless swelling in the jaw. However, it can sometimes cause discomfort, bone expansion, and displacement of teeth.

Diagnosis

Diagnosis of OKC is usually confirmed by histopathological examination. Radiographically, it often appears as a unilocular or multilocular radiolucent lesion.

Treatment

Treatment options for OKC include surgical enucleation, marsupialization, and in some cases, resection.

Prognosis

The prognosis of OKC is generally good, but it has a high recurrence rate, which necessitates long-term follow-up.

Related Terms

• Cyst
• Odontogenic
• Nevoid basal cell carcinoma syndrome
• Histopathology
• Enucleation
• Marsupialization

External links

• Medical encyclopedia article on Odontogenic keratocyst
• Wikipedia's article - Odontogenic keratocyst

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