OR51G2

OR51G2 is a gene that encodes a protein in the olfactory receptor family. This family is a group of G protein-coupled receptors that are involved in the detection of smell. The OR51G2 gene is also known as OR51G2P, and it is located on chromosome 11 in humans.

Function

The OR51G2 gene encodes a member of the olfactory receptor family of proteins. These proteins are part of the G protein-coupled receptor superfamily. They are located in the cell membrane of olfactory sensory neurons, where they detect odorant molecules and initiate a neural response. This response is then transmitted to the brain, resulting in the perception of smell.

Structure

The OR51G2 protein is a transmembrane protein, meaning it spans the cell membrane. It has seven transmembrane domains, which is a characteristic feature of G protein-coupled receptors. The protein also has an extracellular N-terminus and an intracellular C-terminus.

Clinical significance

While the exact role of OR51G2 in human health and disease is not fully understood, olfactory receptors in general are known to play a crucial role in the sense of smell. Mutations in these genes can lead to anosmia, which is the inability to perceive odor.

See also

• Olfactory receptor
• G protein-coupled receptor
• Anosmia

References

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