OR1D2

OR1D2 (also known as Olfactory Receptor Family 1 Subfamily D Member 2) is a protein that in humans is encoded by the OR1D2 gene. It is a member of the olfactory receptor family of genes, which are the largest gene family in the genome.

Function

The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Gene

The OR1D2 gene is located on chromosome 1, specifically 1q44. It spans a length of approximately 1.1 kb and consists of a single exon. The gene is expressed in the olfactory epithelium, where it is believed to play a role in the detection of odorants.

Clinical significance

While the exact role of OR1D2 in human health and disease is not fully understood, olfactory receptors such as OR1D2 are believed to have roles beyond odorant detection. They may be involved in various disease processes, including cancer, metabolic disorders, and neurodegenerative diseases.

See also

• Olfactory receptor
• G protein-coupled receptor
• Gene
• Protein

External links

• OR1D2 at NCBI
• OR1D2 at GeneCards

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