OR13C3

OR13C3 is a gene that encodes a protein in humans. It is also known as Olfactory Receptor Family 13 Subfamily C Member 3. This gene is part of the olfactory receptor family, which is the largest gene family in the genome. The olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell.

Function

The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Clinical significance

While the specific function of OR13C3 is not fully understood, it is believed to play a role in the detection of smell. Mutations in this gene have been associated with a reduction in the sense of smell (anosmia). Further research is needed to fully understand the implications of this gene in human health and disease.

See also

• Olfactory receptor
• Anosmia
• G protein-coupled receptor

External links

• OR13C3 at NCBI
• OR13C3 at GeneCards

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