OR10G6
OR10G6 is a gene that encodes a protein in humans. It is also known as Olfactory Receptor Family 10 Subfamily G Member 6. The OR10G6 gene is part of the olfactory receptor family, which is the largest gene family in the genome. The family members are G-protein coupled receptors that respond to smell and taste stimuli and are responsible for our sense of smell.
Function
The OR10G6 gene provides instructions for making a protein that is part of the olfactory receptor family. These receptors are located on the surface of cells in the nose where they detect odor molecules. Each olfactory receptor protein interacts with specific odor molecules, triggering a signal that is sent to the brain and ultimately interpreted as a distinct smell.
Structure
The OR10G6 gene is located on chromosome 1, specifically on the long (q) arm of chromosome 1 at position 24.2. The exact structure of the OR10G6 protein is not yet known, but like other olfactory receptors, it is likely to have seven transmembrane domains. This is a common structure for proteins that detect signals outside the cell and transmit the signal to the inside of the cell.
Clinical significance
While the exact role of OR10G6 in human health and disease is not yet fully understood, olfactory receptors in general are being studied for their potential roles in disease. For example, some olfactory receptors are expressed in other tissues besides the nose, and may play roles in cancer, metabolism, and other conditions.
See also
References
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Contributors: Prab R. Tumpati, MD