OR10G2

OR10G2 is a gene that encodes a protein in the olfactory receptor family. This family is a group of G protein-coupled receptors which are responsible for detecting odors and pheromones. The OR10G2 gene is specifically involved in the detection of certain odors.

Function

The OR10G2 gene is part of the olfactory receptor family, a group of genes that are expressed in the olfactory epithelium of the nose. These receptors are responsible for the detection of airborne odor molecules and the transduction of these signals to the brain. The OR10G2 gene encodes a protein that is believed to function in this odor detection process.

Structure

The OR10G2 gene is located on chromosome 1, specifically on the long (q) arm at position 24.2. The gene spans approximately 1,000 base pairs and encodes a protein that is 312 amino acids in length. Like other olfactory receptors, the protein encoded by OR10G2 is a G protein-coupled receptor that spans the cell membrane seven times.

Clinical significance

While the specific role of OR10G2 in human health and disease is not well understood, olfactory receptors in general are known to play a role in a variety of physiological and pathological processes. For example, mutations in olfactory receptor genes have been associated with anosmia, a condition characterized by a loss of the sense of smell.

See also

• Olfactory receptor
• G protein-coupled receptor
• Anosmia

References

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