ODAP
ODAP (or β-N-oxalyl-L-α,β-diaminopropionic acid) is a naturally occurring, non-protein amino acid, found in the seeds of the grass pea, Lathyrus sativus, and other Lathyrus species. It is thought to be the causative agent in Lathyrism, a neurological disease that is primarily associated with the consumption of these seeds.
Pronunciation
The pronunciation of ODAP is /ˈoʊdæp/.
Etymology
The term ODAP is an acronym derived from the chemical name of the compound, β-N-oxalyl-L-α,β-diaminopropionic acid.
Related Terms
- Amino Acid: ODAP is a type of non-protein amino acid.
- Lathyrus Sativus: This is the scientific name for the grass pea, the plant in which ODAP is found.
- Lathyrism: A neurological disease caused by the consumption of seeds containing ODAP.
- Neurotoxin: ODAP is considered a neurotoxin, as it can cause damage to the nervous system.
Effects
ODAP is a neurotoxin that can cause a condition known as Lathyrism. This condition is characterized by muscle weakness and paralysis, and is often associated with the consumption of the grass pea, especially during times of famine. The exact mechanism by which ODAP causes these effects is not fully understood, but it is thought to involve the disruption of normal Glutamate signaling in the nervous system.
Prevention and Treatment
The risk of Lathyrism can be reduced by proper preparation of the seeds, such as soaking and boiling, which can reduce the levels of ODAP. There is currently no specific treatment for the effects of ODAP, and management of Lathyrism primarily involves supportive care and physical therapy.
See Also
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