Nucleotide sequence
Nucleotide Sequence
A Nucleotide Sequence is a succession of letters that indicate the order of Nucleotides within a DNA (deoxyribonucleic acid) or RNA (ribonucleic acid) molecule. By convention, sequences are usually presented from the 5' end to the 3' end.
Pronunciation
Nucleotide: /ˈnjuːklɪəˌtaɪd/ Sequence: /ˈsiːkwəns/
Etymology
The term "Nucleotide" was coined in the early 20th century and is derived from the Latin nucleus meaning "kernel" and the Greek tide, a suffix indicating a constituent or particle. "Sequence" comes from the Latin sequentia, meaning "following".
Related Terms
- Base Pair: Two chemical bases bonded to one another forming a "rung of the DNA ladder."
- Genome: The complete set of genes or genetic material present in a cell or organism.
- Genetic Code: The set of rules by which information encoded in genetic material (DNA or RNA sequences) is translated into proteins by living cells.
- Codon: A sequence of three DNA or RNA nucleotides that corresponds with a specific amino acid or stop signal during protein synthesis.
Nucleotide Sequence in Detail
A Nucleotide Sequence is the basic unit of genetic information. Each nucleotide in a sequence corresponds to a genetic code, which is interpreted by cells to produce proteins. The order of the nucleotides in a sequence is critical to the function of the resulting protein.
Nucleotide Sequences are used in Genomics to look for patterns and to compare the DNA of different species. They are also used in Molecular Biology to create synthetic DNA for use in research or therapeutic interventions.
External links
- Medical encyclopedia article on Nucleotide sequence
- Wikipedia's article - Nucleotide sequence
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