Nucleated red blood cell

Nucleated Red Blood Cell (NRBC)

Nucleated Red Blood Cells (NRBCs), also known as normoblasts, are immature red blood cells that contain a nucleus. They are typically found in the bone marrow, but can occasionally be seen in the peripheral blood under certain conditions.

Pronunciation

Nucleated Red Blood Cell: /ˈnjuːklɪeɪtɪd rɛd blʌd sɛl/

Etymology

The term "Nucleated Red Blood Cell" is derived from the Latin "nucleus" meaning "kernel" or "core", and the Old English "blod", meaning "blood". The term "cell" comes from the Latin "cella", meaning "small room".

Related Terms

Erythropoiesis: The process by which red blood cells are produced.
Hematopoiesis: The formation of blood cellular components.
Anemia: A condition marked by a deficiency of red blood cells or of hemoglobin in the blood.
Leukemia: A group of cancers that usually begin in the bone marrow and result in high numbers of abnormal white blood cells.
Bone Marrow: The flexible tissue in the interior of bones where blood cells are made.

Conditions Associated with NRBCs

The presence of NRBCs in the peripheral blood is often associated with severe illness or stress, such as:

Sepsis: A life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs.
Hemolytic Anemia: A condition in which red blood cells are destroyed and removed from the bloodstream before their normal lifespan is over.
Cancer: A group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

External links

Medical encyclopedia article on Nucleated red blood cell
Wikipedia's article - Nucleated red blood cell

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Nucleated red blood cell