Normochromic anemia
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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Normochromic anemia | |
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Synonyms | N/A |
Pronounce | N/A |
Specialty | N/A |
Symptoms | Fatigue, pallor, shortness of breath, dizziness |
Complications | Heart failure, angina, cognitive impairment |
Onset | Varies depending on underlying cause |
Duration | Chronic or acute |
Types | Anemia of chronic disease, aplastic anemia, hemolytic anemia |
Causes | Chronic disease, bone marrow failure, hemolysis |
Risks | Chronic illness, autoimmune disorders, infections |
Diagnosis | Complete blood count, reticulocyte count, bone marrow biopsy |
Differential diagnosis | Microcytic anemia, macrocytic anemia |
Prevention | Depends on underlying cause |
Treatment | Blood transfusion, erythropoiesis-stimulating agents, treatment of underlying cause |
Medication | N/A |
Prognosis | Varies depending on underlying cause |
Frequency | Common in patients with chronic diseases |
Deaths | N/A |
Normochromic anemia is a type of anemia characterized by red blood cells that have a normal concentration of hemoglobin. This condition is distinct from other forms of anemia, such as hypochromic anemia, where the red blood cells have reduced hemoglobin content, and hyperchromic anemia, where there is an increased concentration of hemoglobin.
Causes
Normochromic anemia can result from a variety of underlying conditions. Some of the common causes include:
- Chronic disease: Conditions such as chronic kidney disease, rheumatoid arthritis, and lupus can lead to normochromic anemia.
- Acute blood loss: Sudden loss of blood due to trauma or surgery can result in normochromic anemia.
- Bone marrow disorders: Diseases affecting the bone marrow, such as aplastic anemia or myelodysplastic syndromes, can cause normochromic anemia.
- Hemolytic anemia: This occurs when red blood cells are destroyed faster than they can be produced.
Symptoms
The symptoms of normochromic anemia are similar to those of other types of anemia and may include:
Diagnosis
Diagnosis of normochromic anemia involves a combination of clinical evaluation and laboratory tests. Key diagnostic tests include:
- Complete blood count (CBC): This test measures the levels of red blood cells, hemoglobin, and hematocrit.
- Reticulocyte count: This test assesses the number of young red blood cells in the blood, indicating bone marrow activity.
- Peripheral blood smear: Examination of the blood under a microscope to assess the shape and size of red blood cells.
Treatment
The treatment of normochromic anemia depends on the underlying cause. General approaches include:
- Addressing the underlying condition: Treating the primary disease causing the anemia.
- Blood transfusion: In cases of severe anemia, transfusions may be necessary to restore normal red blood cell levels.
- Erythropoiesis-stimulating agents: These medications can stimulate the production of red blood cells in certain conditions.
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Contributors: Prab R. Tumpati, MD